ea0016p557 | Obesity | ECE2008
Greiling Marie
, Hubold Christian
, Conrad Matthias
, Kuhn Johanna
, Fischer Bernd
, Lehnert Hendrik
, Peters Achim
Obesity, diabetes, and depression are associated with distinct neuroendocrine changes influencing the regulation of the hypothalamus pituitary adrenal (HPA) system. Up to now it was not possible to examine the central glucocorticoid feedback in humans to verify results of animal experiments in relating disease models. With the help of a recently developed computational approach we were enabled to address this question to patients with obesity, diabetes, or depression.<p cl...